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Differential DNA methylation marks and gene comethylation of COPD in African-Americans with COPD exacerbations

5 Nov 2016

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is the third-leading cause of death worldwide. Identifying COPD-associated DNA methylation marks in African-Americans may contribute to our understanding of racial disparities in COPD susceptibility. We determined differentially methylated genes and co-methylation network modules associated with COPD in African-Americans recruited during exacerbations of COPD and...

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PMID: 27814717
DOI: 10.1186/s12931-016-0459-8

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