Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of Bacillus subtilis mutants to produce tryptophan in pigs.

Biotechnology letters - 1 Feb 2017

Bjerre Karin, Cantor Mette D, Nørgaard Jan V, Poulsen Hanne D, Blaabjerg Karoline, Canibe Nuria, Jensen Bent B, Stuer-Lauridsen Birgitte, Nielsen Bea, Derkx Patrick M F

Abstract excerpt

OBJECTIVES: To generate tryptophan-overproducing Bacillus subtilis strains for in situ use in pigs, to reduce the feed cost for farmers and nitrogen pollution. RESULTS: A novel concept has been investigated-to generate B. subtilis strains able to produce tryptophan (Trp) in situ in pigs. Mutagenesis by UV was combined with selection on Trp and purine analogues in an iterative process. Two mutants from different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacillus subtilis
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Mutation

Share to Operon

Share to Tryptophan

Share to Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 27812824
DOI: 10.1007/s10529-016-2245-6
PMCID: PMC5247549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of Bacillus subtilis mutants to produce tryptophan in pigs.PMID 27812824Read ↗

Analyzing the genetic characteristics of a tryptophan-overproducing Escherichia coli.Semantic proximity Read ↗

Establishment of a Biosensor-based High-Throughput Screening Platform for Tryptophan Overproduction.Semantic proximity Read ↗

Intestinal tryptophan metabolism in disease prevention and swine productionSemantic proximity Read ↗

Report: Bioconversion of agriculture waste to lysine with UV mutated strain of brevibacterium flavum and its biological evaluation in broiler chicks.Semantic proximity Read ↗

Cloning of the trp gene cluster from a tryptophan-hyperproducing strain of Corynebacterium glutamicum: identification of a mutation in the trp leader sequence.Semantic proximity Read ↗

Enhancement of L-tryptophan 5-hydroxylation activity by structure-based modification of L-phenylalanine 4-hydroxylase from Chromobacterium violaceum.Semantic proximity Read ↗

Positions of Trp codons in the leader peptide-coding region of the at operon influence anti-trap synthesis and trp operon expression in Bacillus licheniformis.Semantic proximity Read ↗

Variability of the Bacillus anthracis tryptophan operonSemantic proximity Read ↗

PCR mutagenesis and overexpression of tryptophan synthase from Salmonella typhimurium: on the roles of beta2 subunit Lys-382.Semantic proximity Read ↗

A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.Semantic proximity Read ↗

Mutations in the regulatory regions result in increased streptomycin resistance and keratinase synthesis in Bacillus thuringiensis.Semantic proximity Read ↗

High-level expression of Bacillus subtilis tryptophanyl-tRNA synthetase in Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.