Article
Genomic Variants Associated with Resistance to High Fat Diet Induced Obesity in a Primate Model.
Scientific reports - 4 Nov 2016
Harris R Alan, Alcott Callison E, Sullivan Elinor L, Takahashi Diana, McCurdy Carrie E, Comstock Sarah, Baquero Karalee, Blundell Peter, Frias Antonio E, Kahr Maike, Suter Melissa, Wesolowski Stephanie, Friedman Jacob E, Grove Kevin L, Aagaard Kjersti M
Abstract excerpt
Maternal obesity contributes to an increased risk of lifelong morbidity and mortality for both the mother and her offspring. In order to better understand the molecular mechanisms underlying these risks, we previously established and extensively characterized a primate model in Macaca fuscata (Japanese macaque). In prior studies we have demonstrated that a high fat, caloric dense maternal diet structures the...
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