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Article

Genetic and hormonal control of hepatic steatosis in female and male mice.

Journal of lipid research - 1 Jan 2017

Norheim Frode, Hui Simon T, Kulahcioglu Emre, Mehrabian Margarete, Cantor Rita M, Pan Calvin, Parks Brian W, Lusis Aldons J

Abstract excerpt

The etiology of nonalcoholic fatty liver disease is complex and influenced by factors such as obesity, insulin resistance, hyperlipidemia, and sex. We now report a study on sex difference in hepatic steatosis in the context of genetic variation using a population of inbred strains of mice. While male mice generally exhibited higher concentration of hepatic TG levels on a high-fat high-sucrose diet, sex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27811231
DOI: 10.1194/jlr.M071522
PMCID: PMC5234719

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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