Article
Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection.
The Journal of experimental medicine - 14 Nov 2016
Nabekura Tsukasa, Lanier Lewis L
Abstract excerpt
Natural killer (NK) cells provide important host defense and can generate long-lived memory NK cells. Here, by using novel transgenic mice carrying inducible Cre expressed under the control of Ncr1 gene, we demonstrated that two distinct long-lived NK cell subsets differentiate in a mouse model of cytomegalovirus (MCMV) infection. NK cells expressing the MCMV-specific Ly49H receptor differentiated into memory NK...
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