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Article

Memory CD8 T Cells Generated by Cytomegalovirus Vaccine Vector Expressing NKG2D Ligand Have Effector-Like Phenotype and Distinct Functional Features.

Frontiers in immunology - 1 Jan 2021

Šustić Marko, Cokarić Brdovčak Maja, Lisnić Berislav, Materljan Jelena, Juranić Lisnić Vanda, Rožmanić Carmen, Indenbirken Daniela, Hiršl Lea, Busch Dirk H, Brizić Ilija, Krmpotić Astrid, Jonjić Stipan

Abstract excerpt

Viral vectors have emerged as a promising alternative to classical vaccines due to their great potential for induction of a potent cellular and humoral immunity. Cytomegalovirus (CMV) is an attractive vaccine vector due to its large genome with many non-essential immunoregulatory genes that can be easily manipulated to modify the immune response. CMV generates a strong antigen-specific CD8 T cell response with a...

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Source

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Identifiers

PMID: 34168650
DOI: 10.3389/fimmu.2021.681380
PMCID: PMC8218728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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