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Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection

24 Jan 2011

Abstract excerpt

Cells of the immune system undergo homeostatic proliferation during times of lymphopenia induced by certain viral infections or caused by chemotherapy and radiation treatment. Natural killer (NK) cells are no exception and can rapidly expand in number when placed into an environment devoid of these cells. We explored the lifespan and function of mouse NK cells that have undergone homeostatic proliferation in...

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PMID: 21262959
DOI: 10.1084/jem.20100479

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