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Article

Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage.

Stem cells and development - 15 Feb 2017

Raju Ravali, Chau David, Cho Dong Seong, Park Yonsil, Verfaillie Catherine M, Hu Wei-Shou

Abstract excerpt

The differentiation of human pluripotent stem cells toward the hepatocyte lineage can potentially provide an unlimited source of functional hepatocytes for transplantation and extracorporeal bioartificial liver applications. It is anticipated that the quantities of cells needed for these applications will be in the order of 109-1010 cells, because of the size of the liver. An ideal differentiation protocol would...

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Identifiers

PMID: 27806669
DOI: 10.1089/scd.2016.0119
PMCID: PMC5972777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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