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Differentiation of mouse and human embryonic stem cells into hepatic lineages

30 May 2008

Abstract excerpt

We recently reported a novel method to induce embryonic stem (ES) cells differentiate into an endodermal fate, especially pancreatic, using a supporting cell line. Here we describe the modified culture condition with the addition and withdrawal of secreted growth factors could induce ES cells to selectively differentiate into a hepatic fate efficiently. The signaling of BMP and FGF that have been implicated in...

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Liver physiology and pathology
Pancreatic function and diabetes
Pluripotent Stem Cells Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18513331
DOI: 10.1111/j.1365-2443.2008.01201.x

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