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Article

Timing of Physical Activity, Apolipoprotein E ε4 Genotype, and Risk of Incident Mild Cognitive Impairment.

Journal of the American Geriatrics Society - 1 Dec 2016

Krell-Roesch Janina, Pink Anna, Roberts Rosebud O, Stokin Gorazd B, Mielke Michelle M, Spangehl Kathleen A, Bartley Mairead M, Knopman David S, Christianson Teresa J H, Petersen Ronald C, Geda Yonas E

Abstract excerpt

OBJECTIVES: To investigate the timing (mid- vs late life) of physical activity, apolipoprotein (APO)E ε4, and risk of incident mild cognitive impairment (MCI). DESIGN: Prospective cohort study. SETTING: Mayo Clinic Study of Aging (Olmsted County, MN). PARTICIPANTS: Cognitively normal elderly adults (N = 1,830, median age 78, 50.2% female). MEASUREMENTS: Light, moderate, and vigorous physical activities in mid-...

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PMID: 27801933
DOI: 10.1111/jgs.14402
PMCID: PMC5173416

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APOE

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