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Article

Risk and protective factors for cognitive impairment in persons aged 85 years and older.

Neurology - 5 May 2015

Roberts Rosebud O, Cha Ruth H, Mielke Michelle M, Geda Yonas E, Boeve Bradley F, Machulda Mary M, Knopman David S, Petersen Ronald C

Abstract excerpt

OBJECTIVE: To determine risk and protective factors for mild cognitive impairment (MCI) among persons 85 years and older. METHODS: Participants in the population-based prospective Mayo Clinic Study of Aging were comprehensively evaluated at baseline and at 15 monthly intervals to determine incident MCI. At baseline, lifestyle factors in midlife and late life were assessed by self-reported questionnaire; vascular...

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Identifiers

PMID: 25854867
DOI: 10.1212/WNL.0000000000001537
PMCID: PMC4433468

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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