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Potent Inhibition of Human Cytomegalovirus by Modulation of Cellular SNARE Syntaxin 5

20 Oct 2016

Abstract excerpt

Formation of the cytoplasmic viral assembly compartment (cVAC) is an important step for efficient human cytomegalovirus (HCMV) assembly. To do this, the virus must alter and repurpose the normal cellular balance of membrane and protein flux, a process that is not well understood. Although a recent screen identified three viral proteins essential for cVAC formation, less is known about the contribution of cellular...

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PMID: 27795424
DOI: 10.1128/jvi.01637-16

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