Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The utility of ETV 1, ETV 4 and ETV 5 RNA in‐situ hybridization in the diagnosis of CIC – DUX sarcomas

16 Dec 2016

Abstract excerpt

AIMS: A recently characterized group of undifferentiated small round cell sarcomas harbours fusions of the genes CIC and DUX4. Studies report a distinctive gene expression profile for these sarcomas, including expression of E26 transformation-specific (ETS) family proto-oncogenic transcription factors ETV1, ETV4 and ETV5. To test the utility of an ancillary diagnostic technique for these tumours, we evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lymphoma Diagnosis and Treatment
Share to Protein Degradation and Inhibitors
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27790742
DOI: 10.1111/his.13112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The utility of ETV 1, ETV 4 and ETV 5 RNA in‐situ hybridization in the diagnosis of CIC – DUX sarcomasPMID 27790742Read ↗

CIC break‐apart fluorescence in‐situ hybridization misses a subset of CIC – DUX 4 sarcomas: a clinicopathological and molecular studySemantic proximity Read ↗

The CIC-DUX4 fusion oncoprotein drives metastasis and tumor growth via distinct downstream regulatory programs and therapeutic targets in sarcomaSemantic proximity Read ↗

ETV transcriptional upregulation is more reliable than RNA sequencing algorithms and FISH in diagnosing round cell sarcomas with CIC gene rearrangementsSemantic proximity Read ↗

High prevalence of <i>CIC</i> fusion with double‐homeobox (DUX4) transcription factors in <i>EWSR1</i> ‐negative undifferentiated small blue round cell sarcomasSemantic proximity Read ↗

CIC-DUX4 Induces Small Round Cell Sarcomas Distinct from Ewing SarcomaSemantic proximity Read ↗

Ancillary Tools for the Diagnosis of CIC ‐Rearranged Sarcoma: A Comprehensive ReviewSemantic proximity Read ↗

Undifferentiated Small Round Cell Sarcoma With t(4;19)(q35;q13.1) CIC-DUX4 FusionSemantic proximity Read ↗

Detecting disease‐defining gene fusions in unclassified round cell sarcomas using anchored multiplex PCR/targeted RNA next‐generation sequencing—Molecular and clinicopathological characterization of 16 casesSemantic proximity Read ↗

Clinicopathologic Features of CIC-NUTM1 Sarcomas, a New Molecular Variant of the Family of CIC-Fused SarcomasSemantic proximity Read ↗

A novel CIC-FOXO4 gene fusion in undifferentiated small round cell sarcoma: a genetically distinct variant of Ewing-like sarcoma.Semantic proximity Read ↗

NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma.Semantic proximity Read ↗

Clinicopathologic Features of a Series of Primary Renal CIC-rearranged Sarcomas With Comprehensive Molecular Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.