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Article

NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma.

Human pathology - 1 Jul 2017

Sugita Shintaro, Arai Yasuhito, Aoyama Tomoyuki, Asanuma Hiroko, Mukai Wakako, Hama Natsuko, Emori Makoto, Shibata Tatsuhiro, Hasegawa Tadashi

Abstract excerpt

CIC-rearranged sarcoma is a new entity of undifferentiated small round cell sarcoma characterized by chimeric fusions with CIC rearrangement. We report a NUTM2A-CIC fusion sarcoma in a 43-year-old woman who died of rapidly progressive disease. Histologic analysis revealed multinodular proliferation of small round tumor cells with mild nuclear pleomorphism. The sclerotic fibrous septa separated the tumor into...

Topics

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Fatal Outcome
Gene Fusion
Gene Rearrangement
Homeodomain Proteins
In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oncogene Proteins, Fusion

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Identifiers

PMID: 28188754
DOI: 10.1016/j.humpath.2017.01.012

Genes

CIC
ETV4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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