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Article

Clinicopathologic Features of a Series of Primary Renal CIC-rearranged Sarcomas With Comprehensive Molecular Analysis.

The American journal of surgical pathology - 1 Oct 2018

Mangray Shamlal, Kelly David R, LeGuellec Sophie, Fridman Eddie, Aggarwal Sangeeta, Shago Mary, Matoso Andres, Madison Russell, Pramanik Sharmila, Zhong Shan, Li Rong, Lombardo Kara A, Cramer Stuart, Pressey Joseph, Ross Jeffrey S, Corona Robert J, Bratslavsky Gennady, Argani Pedram, Coindre Jean-Michel, Somers Gino R, Ali Siraj M, Yakirevich Evgeny

Abstract excerpt

CIC-rearranged sarcomas rarely occur in visceral organs including the kidney. The most common fusion partner with CIC is the DUX4 gene, but variant fusion partners have also been reported. Herein, we describe the clinicopathologic features and comprehensive molecular profiling of 4 cases of primary renal CIC-rearranged sarcomas. All cases occurred in females, age range 13 to 82 years and included 3 resections and...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29901569
DOI: 10.1097/PAS.0000000000001098

Genes

CIC
DUX4
NUTM1
ETV4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Clinicopathologic Features of a Series of Primary Renal CIC-rearranged Sarcomas With Comprehensive Molecular Analysis.PMID 29901569Read ↗

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