Article
Influence of HLA-DRB1 Alleles on the Variations of Antibody Response to Tuberculosis Serodiagnostic Antigens in Active Tuberculosis Patients.
PloS one - 1 Jan 2016
Zhou Fangbin, Xu Xindong, Wu Sijia, Cui Xiaobing, Fan Lin, Pan Weiqing
Abstract excerpt
Serology-based tests for tuberculosis (TB) diagnosis, though rapid, efficient and easily implemented, have so far shown unsatisfactory levels of sensitivity and specificity, probably due to variations of the antibody response in TB patients. The number and types of seropositive antigens vary from individual to individual. The person-to-person variations of antigen recognition may be linked to genetic...
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