Article

Evidence associating neutrophilia, lung damage, hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality in critically ill COVID-19 patients

2023-09-18

Abstract excerpt

<h4>Background</h4> COVID-19 severity and high in-hospital mortality are often associated with severe hypoxemia, hyperlactatemia, and acidosis. Since neutrophil numbers in severe COVID-19 can exceed 80% of the total circulating leukocytes and that they are massively recruited to infected lungs, we investigated whether metabolic acidosis mediated by the glycolytic neutrophils is associated with lung damage and imp...

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Literature Corpus work: c5fedbfd-1c34-535e-aac0-89aca7b17499
DOI: 10.1101/2023.09.17.558185

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