Article
Genetic Heterogeneity of HER2 Amplification and Telomere Shortening in Papillary Thyroid Carcinoma.
International journal of molecular sciences - 21 Oct 2016
Caria Paola, Cantara Silvia, Frau Daniela Virginia, Pacini Furio, Vanni Roberta, Dettori Tinuccia
Abstract excerpt
Extensive research is dedicated to understanding if sporadic and familial papillary thyroid carcinoma are distinct biological entities. We have previously demonstrated that familial papillary thyroid cancer (fPTC) cells exhibit short relative telomere length (RTL) in both blood and tissues and that these features may be associated with chromosome instability. Here, we investigated the frequency of HER2 (Human...
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