Article
Telomere length in neoplastic and nonneoplastic tissues of patients with familial and sporadic papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism - 1 Nov 2011
Capezzone Marco, Cantara Silvia, Marchisotta Stefania, Busonero Giulia, Formichi Caterina, Benigni Michele, Capuano Serena, Toti Paolo, Pazaitou-Panayiotou Kalliopi, Caruso Giuseppe, Carli Anton Ferdinando, Palummo Nazzareno, Pacini Furio
Abstract excerpt
INTRODUCTION: Many studies have found an association between altered telomere length (TL), both attrition or elongation, and cancer phenotype. Recently, we have reported that patients with the familial form of papillary thyroid cancer (FPTC) have short telomeres in blood leucocytes. AIM: To evaluate relative TL (RTL) at somatic level in neoplastic and nonneoplastic tissues of patients with FPTC (n = 30) and...
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