Article
SREBF-2 polymorphism influences white matter microstructure in bipolar disorder.
Psychiatry research. Neuroimaging - 30 Nov 2016
Poletti Sara, Aggio Veronica, Bollettini Irene, Falini Andrea, Colombo Cristina, Benedetti Francesco
Abstract excerpt
The aim of the study is to investigate if gene polymorphisms in sterol regulatory element binding protein transcriptional factors SREBF-1 and SREBF-2, which regulate lipid and cholesterol metabolism, could affect white matter (WM) microstructure, the most recognized structural biomarker of bipolar disorder (BD). In a sample of 93 patients affected by BD, we investigated the effect of SREBF-1 rs11868035, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
