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Article

Effects of Ca2+ ions on bestrophin-1 surface films.

Colloids and surfaces. B, Biointerfaces - 1 Jan 2017

Mladenova Kirilka, Petrova Svetla D, Andreeva Tonya D, Moskova-Doumanova Veselina, Topouzova-Hristova Tanya, Kalvachev Yuri, Balashev Konstantin, Bhattacharya Shomi S, Chakarova Christina, Lalchev Zdravko, Doumanov Jordan A

Abstract excerpt

Human bestrophin-1 (hBest1) is a transmembrane calcium-activated chloride channel protein - member of the bestrophin family of anion channels, predominantly expressed in the membrane of retinal pigment epithelium (RPE) cells. Mutations in the protein cause ocular diseases, named Bestrophinopathies. Here, we present the first Fourier transform infrared (FTIR) study of the secondary structure elements of hBest1,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27768912
DOI: 10.1016/j.colsurfb.2016.10.023

Genes

AFM
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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