Article
p53 as the main traffic controller of the cell signaling network.
Frontiers in bioscience (Landmark edition) - 1 Jun 2010
Sebastian Sinto, Azzariti Amalia, Silvestris Nicola, Porcelli Letizia, Russo Antonio, Paradiso Angelo
Abstract excerpt
Among different pathological conditions that affect human beings, cancer has received a great deal of attention primarily because it leads to significant morbidity and mortality. This is essentially due to increasing world-wide incidence of this disease and the inability to discover the cause and molecular mechanisms by which normal human cells acquire the characteristics that define cancer cells. Since the...
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