Article
Ovarian cancer: new developments in clear cell carcinoma and hopes for targeted therapy.
Japanese journal of clinical oncology - 1 May 2015
Yamashita Yoriko
Abstract excerpt
Until recently, ovarian clear cell carcinoma was recognized by its unique morphology and unfavorable patient outcome primarily due to tumor chemoresistance. Recently, specific molecular characteristics of ovarian clear cell carcinoma, such as PI3CA mutation, ARID1a mutation and MET amplification, have been elucidated. In addition, an association between endometriosis and the tumor has also been a focus of...
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