Article
Radiation, DNA damage and cancer.
Molecular medicine today - 1 Apr 1999
Hall J, Angèle S
Abstract excerpt
The characterization of the rare, radiation-sensitive and cancer-prone syndromes, ataxia telangiectasia and Nijmegen breakage syndrome, has demonstrated that genetic predisposition increases the risk of developing cancer after exposure to ionizing radiation (IR). Molecular analyses of these disorders provide valuable insights into the normal function of these two gene products in the cellular response to...
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