Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation-Specific Differences in Kv7.1 (KCNQ1) and Kv11.1 (KCNH2) Channel Dysfunction and Long QT Syndrome Phenotypes.

International journal of molecular sciences - 2 Jul 2022

Kekenes-Huskey Peter M, Burgess Don E, Sun Bin, Bartos Daniel C, Rozmus Ezekiel R, Anderson Corey L, January Craig T, Eckhardt Lee L, Delisle Brian P

Abstract excerpt

The electrocardiogram (ECG) empowered clinician scientists to measure the electrical activity of the heart noninvasively to identify arrhythmias and heart disease. Shortly after the standardization of the 12-lead ECG for the diagnosis of heart disease, several families with autosomal recessive (Jervell and Lange-Nielsen Syndrome) and dominant (Romano-Ward Syndrome) forms of long QT syndrome (LQTS) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac electrophysiology and arrhythmias
Share to Electrocardiography

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to ERG1 Potassium Channel

Share to Ion channel regulation and function

Share to KCNQ1 Potassium Channel

Share to Mutation

Share to Phenotype

Share to Romano-Ward Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 35806392
DOI: 10.3390/ijms23137389
PMCID: PMC9266926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation-Specific Differences in Kv7.1 (KCNQ1) and Kv11.1 (KCNH2) Channel Dysfunction and Long QT Syndrome Phenotypes.PMID 35806392Read ↗

The long QT syndrome: ion channel diseases of the heart.Semantic proximity Read ↗

Inherited long QT syndrome: clinical manifestation, genetic diagnostics, and therapy.Semantic proximity Read ↗

Congenital long QT syndrome: a clinician's guide.Semantic proximity Read ↗

Inherited ion channel diseases: a brief review.Semantic proximity Read ↗

Clinical and genetic diagnosis for inherited cardiac arrhythmias.Semantic proximity Read ↗

Diagnosis, management and therapeutic strategies for congenital long QT syndrome.Semantic proximity Read ↗

KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?Semantic proximity Read ↗

Pathogenesis and Clinical Characteristics of Hereditary Arrhythmia Diseases.Semantic proximity Read ↗

Potassium-channel mutations and cardiac arrhythmias--diagnosis and therapy.Semantic proximity Read ↗

Genetic basis of malignant channelopathies and ventricular fibrillation in the structurally normal heart.Semantic proximity Read ↗

Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function.Semantic proximity Read ↗

Mutation-specific pharmacology of the long QT syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.