Replication of associations between genetic polymorphisms and chronic graft-versus-host disease.

doi:10.1182/blood-2016-07-728063

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Article

Replication of associations between genetic polymorphisms and chronic graft-versus-host disease.

Blood - 17 Nov 2016

Martin Paul J, Fan Wenhong, Storer Barry E, Levine David M, Zhao Lue Ping, Warren Edus H, Flowers Mary E D, Lee Stephanie J, Carpenter Paul A, Boeckh Michael, Hingorani Sangeeta, Yan Li, Hu Qiang, Preus Leah, Liu Song, Spellman Stephen, Zhu Xiaochun, Pasquini Marcelo, McCarthy Philip, Stram Daniel, Sheng Xin, Pooler Loreall, Haiman Christopher A, Sucheston-Campbell Lara, Hahn Theresa, Hansen John A

Abstract excerpt

Previous studies have identified single-nucleotide polymorphisms (SNPs) associated with the risk of chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation. The current study determined whether these associations could be replicated in large cohorts of donors and recipients. Each SNP was tested with cohorts of patients having the same donor type (HLA-matched related,...

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Identifiers

PMID: 27758874
DOI: 10.1182/blood-2016-07-728063
PMCID: PMC5114491

Genes

CCR6
CTLA4
HPSE

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