Article
Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation.
Bone marrow transplantation - 1 May 2017
Berro M, Palau Nagore M V, Rivas M M, Longo P, Foncuberta C, Vitriú A, Remaggi G, Martínez Rolon J, Jaimovich G, Requejo A, Feldman L, Padros K, Rodríguez M B, Shaw B E, Larripa I, Belli C B, Kusminsky G D
Abstract excerpt
Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematological malignancies. Numerous genetic factors have a role in transplant outcome. Several functional polymorphisms have been identified in TGF-β1 gene, such as single-nucleotide polymorphism (SNP) at +29C>T within exon 1. Two hundred and forty five patient/donor pairs who underwent a...
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