Article
Association of tumor necrosis factor-α (TNF-α) gene promoter polymorphisms with aggressive and chronic periodontitis in the eastern Indian population.
Bioscience reports - 31 Aug 2018
Majumder Poulami, Thou Keheibamding, Bhattacharya Mandar, Nair Vineet, Ghosh Sujay, Dey Subrata Kumar
Abstract excerpt
Background: Periodontitis is a very common inflammatory oral disease. Tumor necrosis factor-α (TNF-α) is a cytokine that has been involved with the gingival tissue destruction and remodeling occurrence. We investigated the association of single nucleotide polymorphisms (SNPs) in TNF-α gene promoter region with the susceptibility of aggressive and chronic periodontitis in the eastern Indian population.Methods: A...
Topics
- Adolescent
- Adult
- Aged
- Asian People
- Chronic Periodontitis
- Female
- Gene Frequency
- Genotype
- Humans
- India
- Male
- Middle Aged