Article
TCF7L2 and CCND1 polymorphisms and its association with colorectal cancer in Mexican patients.
Cellular and molecular biology (Noisy-le-Grand, France) - 30 Sept 2016
Rosales-Reynoso M A, Arredondo-Valdez A R, Juárez-Vázquez C I, Wence-Chavez L I, Barros-Núñez P, Gallegos-Arreola M P, Flores-Martínez S E, Morán-Moguel M C, Sánchez-Corona J
Abstract excerpt
Accumulative evidence suggests that alterations due to mutations or genetic polymorphisms in the TCF7L2 and CCND1 genes, which are components of the Wnt signaling pathway, contributes to carcinogenesis. The present study was designated to clarify whether common single nucleotide polymorphisms (SNPs) of the transcription factor 7- like 2 (TCF7L2) and cyclin D1 (CCND1) genes are associated with colorectal cancer...
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