Article
NME1 and DCC variants are associated with susceptibility and tumor characteristics in Mexican patients with colorectal cancer.
Journal of the Egyptian National Cancer Institute - 1 Apr 2024
Márquez-González Rosa María, Saucedo-Sariñana Anilú Margarita, de Jesús Tovar-Jacome César, Barros-Núñez Patricio, Gallegos-Arreola Martha Patricia, Orozco-Gutiérrez Mario Humberto, Mariscal-Ramírez Ignacio, Pineda-Razo Tomas Daniel, Alcaraz-Wong Aldo Antonio, Marín-Contreras María Eugenia, Rosales-Reynoso Mónica Alejandra
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) ranks third in cancer incidence globally and is the second leading cause of cancer-related mortality. The nucleoside diphosphate kinase 1 (NME1) and netrin 1 receptor (DCC) genes have been associated with resistance against tumorigenesis and tumor metastasis. This study investigates the potential association between NME1 (rs34214448 G > T and rs2302254 C > T) and DCC (rs2229080...
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