Article
Non-invasive Prenatal Diagnosis of Feto-Maternal Platelet Incompatibility by Cold High Resolution Melting Analysis.
Advances in experimental medicine and biology - 1 Jan 2016
Ferro Marta, Macher Hada C, Noguerol Pilar, Jimenez-Arriscado Pilar, Molinero Patrocinio, Guerrero Juan M, Rubio Amalia
Abstract excerpt
Fetal and Neonatal alloimmune thrombocytopenia (FNAIT) is a condition which could occur when pregnant women develop an alloimmunization against paternally inherited antigens of the fetal platelets. Approximately 80 % of FNAIT cases are caused by anti-HPA-1a, about 15 % by anti-HPA-5b and 5 % by other HPA antibodies. Only 2 % of the total population is HPA-1a negative (HPA-1b1b). The HPA-1a allele differs by one...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
