Article
Antenatal screening for human platelet antigen-1a: results of a prospective study at a large maternity hospital in Ireland.
BJOG : an international journal of obstetrics and gynaecology - 1 May 2003
Davoren Anne, McParland Peter, Crowley John, Barnes Anthony, Kelly Gabrielle, Murphy William G
Abstract excerpt
OBJECTIVE: Fetomaternal mismatch for human platelet antigen (HPA)-1a accounts for approximately 85% of cases of neonatal alloimmune thrombocytopenia. The purpose of the study was to determine the prevalence of the HPA-1a negative platelet phenotype in a cohort of pregnant women in Ireland, the rate of alloimmunisation to HPA-1a in HPA-1 mismatched pregnancies and the associated incidence of neonatal alloimmune...
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