Article
A new efficient tool for non-invasive diagnosis of fetomaternal platelet antigen incompatibility.
British journal of haematology - 1 Sept 2020
Ouzegdouh Mammasse Yasmine, Chenet Christophe, Drubay Damien, Martageix Corinne, Cartron Jean-Pierre, Vainchenker William, Petermann Rachel
Abstract excerpt
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the consequence of platelet destruction by maternal alloantibodies against fetal human platelet antigens (HPA). This may result in intracranial haemorrhages (ICH) or even fetal death. Currently, fetal HPA genotyping is performed using invasive procedures. Here, we carried out a proof-of-concept study for non-invasive prenatal diagnosis of fetal platelet...
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