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Article

Mesothelioma families without inheritance of a BAP1 predisposing mutation.

Cancer genetics - 1 Sept 2016

Ascoli Valeria, Cozzi Ilaria, Vatrano Simona, Izzo Stefania, Giorcelli Jessica, Romeo Elisa, Carnovale-Scalzo Caterina, Grillo Lucia Rosalba, Facciolo Francesco, Visca Paolo, Papotti Mauro, Righi Luisella

Abstract excerpt

Familial malignant mesothelioma clusters are ideal candidates to explore BAP1 genomic status as a predisposing risk factor. We report data on BAP1 analysis in four families with multiple mesothelioma cases to investigate possible BAP1 alterations associated with an inherited cancer syndrome. We also recorded family history of cancer and assessed asbestos exposure. By genomic direct sequencing, we found no...

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Source

Identifiers

PMID: 27751355
DOI: 10.1016/j.cancergen.2016.07.002

Genes

BAP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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