Article
Association of Neuropeptide-Y (NPY) and Interleukin-1beta (IL1B), Genotype-Phenotype Correlation and Plasma Lipids with Type-II Diabetes.
PloS one - 1 Jan 2016
Patel Roma, Dwivedi Mitesh, Mansuri Mohmmad Shoab, Ansarullah, Laddha Naresh C, Thakker Ami, Ramachandran A V, Begum Rasheedunnisa
Abstract excerpt
BACKGROUND: Neuropeptide Y (NPY) is known to play a role in the regulation of satiety, energy balance, body weight, and insulin release. Interleukin-1beta (IL1B) has been associated with loss of beta-cell mass in type-II diabetes (TIID). OBJECTIVES: The present study attempts to investigate the association of NPY exon2 +1128 T/C (Leu7Pro; rs16139), NPY promoter -399 T/C (rs16147) and IL1B -511 C/T (rs16944)...
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