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Article

Association of neuropeptide Y (NPY), interleukin-1B (IL1B) genetic variants and correlation of IL1B transcript levels with vitiligo susceptibility.

PloS one - 1 Jan 2014

Laddha Naresh C, Dwivedi Mitesh, Mansuri Mohmmad Shoab, Singh Mala, Patel Hetanshi H, Agarwal Nishtha, Shah Anish M, Begum Rasheedunnisa

Abstract excerpt

BACKGROUND: Vitiligo is a depigmenting disorder resulting from loss of functional melanocytes in the skin. NPY plays an important role in induction of immune response by acting on a variety of immune cells. NPY synthesis and release is governed by IL1B. Moreover, genetic variability in IL1B is reported to be associated with elevated NPY levels. OBJECTIVES: Aim of the present study was to explore NPY promoter...

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Identifiers

PMID: 25221996
DOI: 10.1371/journal.pone.0107020
PMCID: PMC4164539

Genes

NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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