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The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability

12 Oct 2016

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is responsible for the disease cystic fibrosis (CF). It is a membrane protein belonging to the ABC transporter family functioning as a chloride/anion channel in epithelial cells around the body. There are over 1500 mutations that have been characterised as CF-causing; the most common of these, accounting for ~70 % of CF cases, is the deletion of a...

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Share to Advanced biosensing and bioanalysis techniques
Share to Cystic Fibrosis Research Advances
Share to Neonatal Respiratory Health Research

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PMID: 27734094
DOI: 10.1007/s00018-016-2386-8

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