The cystic fibrosis gene and its product CFTR.

doi:10.1006/scel.1993.1005

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Article

The cystic fibrosis gene and its product CFTR.

Seminars in cell biology - 1 Feb 1993

Harris A, Argent B E

Abstract excerpt

Cystic fibrosis is the commonest, fatal, inherited disease of caucasian populations occurring with a frequency of 1 in 2000 live births. The CF gene spans about 230 kb of genomic DNA and encodes a protein of 1480 amino acids named the cystic fibrosis transmembrane conductance regulator (CFTR). Th...

Topics

Chloride Channels
Chromosome Mapping
Cyclic AMP
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Humans
Ion Channels
Membrane Proteins
Mutation

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