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Article

Association of Polymorphisms in NHEJ Pathway Genes with HIV-1 Infection and AIDS Progression in a Northern Chinese MSM Population.

Disease markers - 1 Jan 2022

Zhang Xuelong, Wang Xi, Mo Han, Hu Yuanting, Yang Yi, Yang Xun, Wu Jiawei, Liu Bangquan, Xu Lidan, Sun Haiming, Jia Xueyuan, Wang Ping, Wang Kaili, Sun Wenjing, Fu Songbin, Qiao Yuandong

Abstract excerpt

Background and Aims: Men who have sex with men (MSM) are at high risk of HIV infection. The nonhomologous end joining (NHEJ) pathway is the main way of double-stranded DNA break (DSB) repair in the higher eukaryotes and can repair the DSB timely at any time in cell cycle. It is also indicated that the NHEJ pathway is associated with HIV-1 infection since the DSB in host genome DNA occurs in the process of HIV-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36312587
DOI: 10.1155/2022/5126867
PMCID: PMC9605847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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