Article
Gene × Environment Interactions in Schizophrenia: Evidence from Genetic Mouse Models.
Neural plasticity - 1 Jan 2016
Moran Paula, Stokes Jennifer, Marr Julia, Bock Gavin, Desbonnet Lieve, Waddington John, O'Tuathaigh Colm
Abstract excerpt
The study of gene × environment, as well as epistatic interactions in schizophrenia, has provided important insight into the complex etiopathologic basis of schizophrenia. It has also increased our understanding of the role of susceptibility genes in the disorder and is an important consideration as we seek to translate genetic advances into novel antipsychotic treatment targets. This review summarises data...
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