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Article

Genetic mouse models relevant to schizophrenia: taking stock and looking forward.

Neuropharmacology - 1 Mar 2012

Harrison Paul J, Pritchett David, Stumpenhorst Katharina, Betts Jill F, Nissen Wiebke, Schweimer Judith, Lane Tracy, Burnet Philip W J, Lamsa Karri P, Sharp Trevor, Bannerman David M, Tunbridge Elizabeth M

Abstract excerpt

Genetic mouse models relevant to schizophrenia complement, and have to a large extent supplanted, pharmacological and lesion-based rat models. The main attraction is that they potentially have greater construct validity; however, they share the fundamental limitations of all animal models of psychiatric disorder, and must also be viewed in the context of the uncertain and complex genetic architecture of...

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PMID: 21864547
DOI: 10.1016/j.neuropharm.2011.08.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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