Article
Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review.
Schizophrenia research - 1 Nov 2013
Modinos Gemma, Iyegbe Conrad, Prata Diana, Rivera Margarita, Kempton Matthew J, Valmaggia Lucia R, Sham Pak C, van Os Jim, McGuire Philip
Abstract excerpt
The relatively high heritability of schizophrenia suggests that genetic factors play an important role in the etiology of the disorder. On the other hand, a number of environmental factors significantly influence its incidence. As few direct genetic effects have been demonstrated, and there is considerable inter-individual heterogeneity in the response to the known environmental factors, interactions between...
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