Article
Th17 Cells Exhibit Antitumor Effects in MDS Possibly through Augmenting Functions of CD8+ T Cells.
Journal of immunology research - 1 Jan 2016
Li Jing, Yue Lanzhu, Wang Huaquan, Liu Chunyan, Liu Hui, Tao Jinglian, Qi Weiwei, Wang Yihao, Zhang Wei, Fu Rong, Shao Zonghong
Abstract excerpt
Th17 cells are a newly found subset of distinct CD4+ Th effector cells' family and are found to play an important role in cancers. Myelodysplastic syndromes (MDS) are a common malignant hematological disease. Here, we showed that both the percentage and the function of Th17 cells were elevated in low-risk MDS while being decreased in high-risk MDS. Levels of upstream molecules of Th17 cells, IL-6 and IL-23, were...
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