Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of two CD4 alleles in Microminipigs.

BMC veterinary research - 7 Oct 2016

Matsubara Tatsuya, Nishii Naohito, Takashima Satoshi, Takasu Masaki, Imaeda Noriaki, Aiki-Oshimo Kayo, Yamazoe Kazuaki, Kakisaka Michinori, Takeshima Shin-Nosuke, Aida Yoko, Kametani Yoshie, Kulski Jerzy K, Ando Asako, Kitagawa Hitoshi

Abstract excerpt

BACKGROUND: We previously identified two phenotypes of CD4+ cells with and without reactions to anti-pig CD4 monoclonal antibodies by flow cytometry in a herd of Microminipigs. In this study, we analyzed the coding sequences of CD4 and certified the expression of CD4 molecules in order to identify the genetic sequence variants responsible for the positive and negative PBMCs reactivity to anti-pig CD4 monoclonal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to CD4 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to RNA, Messenger

Share to Swine, Miniature

Source

Open in PubMed Open full text

Identifiers

PMID: 27717346
DOI: 10.1186/s12917-016-0856-8
PMCID: PMC5055687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of two CD4 alleles in Microminipigs.PMID 27717346Read ↗

Identification of a CD4 variant in Microminipigs not detectable with available anti-CD4 monoclonal antibodies.Semantic proximity Read ↗

Preparation and characterization of monoclonal antibodies recognizing two CD4 isotypes of Microminipigs.Semantic proximity Read ↗

Three functional mutation sites affect the immune response of pigs through altering the expression pattern and IgV domain of the CD4 protein.Semantic proximity Read ↗

Distribution of the CD4 Alleles in Sus scrofa Demonstrates the Genetic Profiles of Western Breeds and Miniature Pigs.Semantic proximity Read ↗

Impact of a CD4 gene haplotype on the immune response in minipigs.Semantic proximity Read ↗

Lack of variation in alphaGal expression on lymphocytes in miniature swine of different genotypes.Semantic proximity Read ↗

The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipigSemantic proximity Read ↗

CD4 bovine gene: Differential polymorphisms among cattle breeds and a new tool for rapid identification.Semantic proximity Read ↗

Next Generation Sequencing of the Pig αβ TCR Repertoire Identifies the Porcine Invariant NKT Cell ReceptorSemantic proximity Read ↗

Swine leukocyte antigen class II genes (SLA-DRA, SLA-DRB1, SLA-DQA, SLA-DQB1) polymorphism and genotyping in Guizhou minipigs.Semantic proximity Read ↗

How the wild things are: comparative T cell phenotyping and memory T cell identification in wild boar and domestic pigs.Semantic proximity Read ↗

A new polymorphic epitope of bovine CD4 antigen evidenced by flow cytometry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.