Article
Preparation and characterization of monoclonal antibodies recognizing two CD4 isotypes of Microminipigs.
PloS one - 1 Jan 2020
Ohshima Shino, Matsubara Tatsuya, Miyamoto Asuka, Shigenari Atsuko, Imaeda Noriaki, Takasu Masaki, Tanaka Masafumi, Shiina Takashi, Suzuki Shingo, Hirayama Noriaki, Kitagawa Hitoshi, Kulski Jerzy K, Ando Asako, Kametani Yoshie
Abstract excerpt
Cluster of differentiation 4 (CD4) molecule expressed on the leukocytes is known to function as a co-receptor for class II major histocompatibility complex (MHC) binding to T cell receptor (TCR) on helper T cells. We previously identified two CD4 alleles (CD4.A and CD4.B) in a Microminipig population based on nucleotide sequencing and PCR detection of their gene sequences. However, CD4.B protein expression was...
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