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Article

Young investigator challenge: Can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next-generation sequencing of thyroid FNA samples?

Cancer cytopathology - 1 Nov 2016

Bellevicine Claudio, Sgariglia Roberta, Malapelle Umberto, Vigliar Elena, Nacchio Mariantonia, Ciancia Giuseppe, Eszlinger Markus, Paschke Ralf, Troncone Giancarlo

Abstract excerpt

BACKGROUND: Fine-needle aspiration (FNA) cytology is accurate and cost-effective in the evaluation of thyroid nodules. Molecular techniques may contribute to risk stratification in indeterminate cases. Although next-generation sequencing (NGS) is a promising technique for the molecular testing of thyroid FNA specimens, thyroid-specific cancer gene panels are not commercially available. Conversely, the Ion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27717198
DOI: 10.1002/cncy.21780

Genes

BRAF
NRAS
RET
HRAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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