Article
Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay.
Cancer - 1 Dec 2014
Nikiforov Yuri E, Carty Sally E, Chiosea Simon I, Coyne Christopher, Duvvuri Umamaheswar, Ferris Robert L, Gooding William E, Hodak Steven P, LeBeau Shane O, Ohori N Paul, Seethala Raja R, Tublin Mitchell E, Yip Linwah, Nikiforova Marina N
Abstract excerpt
BACKGROUND: Fine-needle aspiration (FNA) cytology is a common approach to evaluating thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers the appropriate management of these patients. Follicular (or oncocytic) neoplasm/suspicious for a follicular (or oncocytic) neoplasm (FN/SFN) is a common indeterminate diagnosis with a cancer risk of approximately 15% to 30%. In this study,...
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