Article
Expressed alleles of imprinted IGF2, DLK1 and MEG3 colocalize in 3D-preserved nuclei of porcine fetal cells.
BMC cell biology - 1 Oct 2016
Lahbib-Mansais Yvette, Barasc Harmonie, Marti-Marimon Maria, Mompart Florence, Iannuccelli Eddie, Robelin David, Riquet Juliette, Yerle-Bouissou Martine
Abstract excerpt
BACKGROUND: To explore the relationship between spatial genome organization and gene expression in the interphase nucleus, we used a genomic imprinting model, which offers parental-specific gene expression. Using 3D FISH in porcine fetal liver cells, we compared the nuclear organization of the two parental alleles (expressed or not) of insulin-like growth factor 2 (IGF2), a paternally imprinted gene located on...
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