Article
The AIRN lncRNA is imprinted and paternally expressed in pigs.
Journal of animal science - 3 Jan 2023
Ahn Jinsoo, Hwang In-Sul, Park Mi-Ryung, Hwang Seongsoo, Cho In-Cheol, Lee Kichoon
Abstract excerpt
Genomic imprinting plays critical roles during the development of mammalian species and underlying epigenetic mechanisms frequently involve long non-coding RNAs (lncRNAs). The paternal transcription of the antisense Igf2r RNA noncoding (Airn) is responsible for paternal silencing of the mouse insulin-like growth factor 2 receptor (Igf2r) gene and maternal Igf2r expression. Although the corresponding maternal DNA...
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