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Substrate profiling of Zika virus NS 2B‐ NS 3 protease

1 Oct 2016

Abstract excerpt

Zika virus (ZIKV), isolated from macaques in Uganda in 1947, was not considered to be a dangerous human pathogen. However, this view has recently changed as ZIKV infections are now associated with serious pathological disorders including microcephaly and Guillain–Barré syndrome. Similar to other viruses in the Flaviviridae family, ZIKV expresses the serine protease NS3 which is responsible for viral protein...

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PMID: 27714789
DOI: 10.1002/1873-3468.12443

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